Queen Square · London

Complex OCD Clinic

Private Practice of Dr Himanshu Tyagi

Neuropsychiatrist & Medical Psychotherapist in Cognitive Behavioural Therapy, specialist in treatment of Complex OCD

Research

Over ninety research outputs and 870+ citations on the treatment and neuroscience of OCD

My research follows the three ways OCD is treated. I have written on how medication should be used and combined, on the behavioural treatments for OCD and tics and how to deliver them well and, from the first UK randomised trial of deep brain stimulation for OCD, which I coordinated, to international work mapping the brain circuits that every effective treatment acts upon, on the neuroscience that ties them together. A selection follows in each area; the full list is on Google Scholar and ORCID.

OCD Pharmacotherapy

Current Psychiatry Reviews, 2010

Treatment for Obsessive Compulsive Disorder

Tyagi H, Drummond LM, Fineberg NA.

European Neuropsychopharmacology, 2017

Aripiprazole Augmentation in Profound, SRI-Refractory Obsessive-Compulsive Disorder

Pampaloni I, Khan M, Tyagi H, Drummond LM.

BJPsych Open, 2021

Pharmacological Management of Tourette's Syndrome Comorbid with Obsessive-Compulsive Disorder in Adult Patients

Tyagi H, Ogunbiyi O.

Journal of Neurology, Neurosurgery & Psychiatry, 2020

Case Report of Sertraline Exacerbation of Tics in Tourette's with OCD

Paramlall M, Tyagi H.

Value in Health, 2025

Deep Brain Stimulation: A Cost-Saving Treatment Option for Extreme Treatment-Refractory Obsessive-Compulsive Disorder in the UK?

McLean A, Porteous A, Wright S, et al. (incl. Tyagi H).

OCD Psychotherapy

Comprehensive Psychiatry, 2022

The Global Assessment of OCD

Pampaloni I, Marriott S, Pessina E, Fisher C, Govender A, Mohamed H, Chandler A, Tyagi H, Morris L, Pallanti S.

Journal of Neurology, Neurosurgery & Psychiatry, 2025

Habit Reversal: Two Years On at a Tertiary-Care Hospital

Patel D, Tyagi H.

Indian Journal of Psychiatry, 2026

Behavioural Treatment of Tic Spectrum Disorders: Evolution, Efficacy and Current Best Practice

Patel D, Tyagi H.

Indian Journal of Psychiatry, 2026

From Premonitory Urge to Obsessional Drive: Clinical Nuances of Tourettic Obsessive-Compulsive Disorder

Patel D, Tyagi H.

European Psychiatry, 2025

Gilles de la Tourette Syndrome and Habit Reversal: A Case Report

Patel D, Tyagi H.

Psychiatry Journal, 2015

Comparative Prevalence of Eating Disorders in Obsessive-Compulsive Disorder and Other Anxiety Disorders

Tyagi H, Patel R, Rughooputh F, Abrahams H, Watson AJ, Drummond L.

OCD Neuroscience

Biological Psychiatry, 2019

A Randomized Trial Directly Comparing Ventral Capsule and Anteromedial Subthalamic Nucleus Stimulation in Obsessive-Compulsive Disorder

Tyagi H, Apergis-Schoute AM, Akram H, Foltynie T, Limousin P, Drummond LM, Fineberg NA, et al.

Nature Neuroscience, 2024

Mapping Dysfunctional Circuits in the Frontal Cortex Using Deep Brain Stimulation

Hollunder B, Ostrem JL, Sahin IA, Rajamani N, Oxenford S, Butenko K, et al. (incl. Tyagi H).

Biological Psychiatry, 2024

Deep Brain Stimulation for Obsessive-Compulsive Disorder: Optimal Stimulation Sites

Meyer GM, Hollunder B, Li N, Butenko K, Dembek TA, Hart L, et al. (incl. Tyagi H).

Nature Medicine, 2022

Deep Brain Stimulation for Obsessive-Compulsive Disorder: A Crisis of Access

Visser-Vandewalle V, Andrade P, Mosley PE, Greenberg BD, Schuurman R, et al. (incl. Tyagi H).

medRxiv, 2025

A Multi-Symptom Circuit Architecture of Obsessive-Compulsive Disorder

Hollunder B, Meyer GM, Li N, et al. (incl. Tyagi H).

Movement Disorders, 2025

Anterior Pallidal Stimulation for Severe Tourette Syndrome: Open Phase Outcomes

Limousin P, Foltynie T, Lind V, et al. (incl. Tyagi H).

British Journal of Psychiatry, 2026

Cutting Through Stigma: Psychiatry and Neurosurgery Working Together

Zrinzo L, Huys Q, Howard R, et al. (incl. Tyagi H).

Biological Psychiatry: Global Open Science, 2026

The Occipital-Fronto-Limbic Circuit of Body Dysmorphic Disorder: A Systematic Review and Meta-Analysis

Cheng Y, Burrows E, Zrinzo L, et al. (incl. Tyagi H).